J Colloid Interface Sci. 2026 Apr 4;717:140416. doi: 10.1016/j.jcis.2026.140416. Online ahead of print. ABSTRACT Metal-organic framework (MOF) nanozymes serve as promising biomimetic interfaces for biocatalysis, yet bulk three-dimensional (3D)-MOFs still suffer from insufficient active site accessibility and unclear catalytic mechanisms. Herein, this study reported the rational design of an ultrathin two-dimensional (2D) single-atom MOF nanozyme,…

Bioresour Technol. 2026 Apr 5:134568. doi: 10.1016/j.biortech.2026.134568. Online ahead of print. ABSTRACT ω-Transaminases (ω-TAs) exhibit remarkable efficiency and stereoselectivity in catalyzing the asymmetric synthesis of chiral amines, rendering them prime biocatalysts for pharmaceutical chiral intermediate production. Nevertheless, developing a generalizable strategy to significantly enhance the acceptance of bulky substrates across different ω-TAs remains a major…

Bioorg Chem. 2026 Apr 3;175:109836. doi: 10.1016/j.bioorg.2026.109836. Online ahead of print. ABSTRACT Organophosphates (OPs), widely used as insecticides, exhibit severe acute toxicity and pose a significant threat to public health. Current standard therapy, which mainly relies on atropine and oxime reactivators, alleviates symptoms but fails to effectively eliminate circulating toxin or excess acetylcholine (ACh), thus…

Enzyme Microb Technol. 2026 Apr 3;198:110869. doi: 10.1016/j.enzmictec.2026.110869. Online ahead of print. ABSTRACT Microbial lipases are multifaceted biological catalyst that have surfaced as a key driver in various industries and are both eco-friendly and cost efficient.In large scale applications, lipases produced from bacteria, fungi and yeasts function better than their equivalents generated from plants and…

Chem Rev. 2026 Apr 7. doi: 10.1021/acs.chemrev.5c01010. Online ahead of print. ABSTRACT Biosolar conversion harnesses the complementary advantages of photo(electro)catalysis and redox biocatalysis to synthesize fuels and high-value compounds under sunlight. By routing renewable energy inputs through photo(electro)catalytic interfaces to biocatalysts, nature-inspired biosolar systems achieve highly selective and low-carbon chemical synthesis. This integration transcends the…

Bioresour Technol. 2026 Apr 4:134527. doi: 10.1016/j.biortech.2026.134527. Online ahead of print. ABSTRACT Scaffold-mediated yeast surface display enhances enzyme-enzyme proximity and substrate channel efficiency through the spatial self-assembly of enzyme molecules, overcoming limitations such as enzyme dispersion and mass transfer in traditional multi-enzyme systems. Despite its potential in biocatalysis, existing scaffold systems face challenges, including large…

J Adv Res. 2026 Apr 4:S2090-1232(26)00283-3. doi: 10.1016/j.jare.2026.04.004. Online ahead of print. ABSTRACT INTRODUCTION: Inducing the development of disease-suppressive soils against root-knot nematodes (RKNs) represents a sustainable strategy for reducing pesticide dependence, with microbial management serving as a core approach. However, the formation mechanisms, key microbial drivers, and functional stability of RKN disease suppressive soil…

Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2522978123. doi: 10.1073/pnas.2522978123. Epub 2026 Apr 6. ABSTRACT Nonsegmented negative-sense RNA viruses (nsNSVs) rely on a multifunctional RNA-dependent RNA polymerase (RdRP) complex for transcription and replication. In measles virus (MeV), the nonstructural protein C has long been implicated in regulating RNA synthesis, yet its precise role…