Educating and Building a Broader Biocatalysis Community
Biotechnol Biofuels Bioprod. 2026 Apr 3. doi: 10.1186/s13068-026-02755-5. Online ahead of print. ABSTRACT Flavin-dependent monooxygenases (FMOs) are versatile oxidative biocatalysts that catalyze a wide array of oxygenation reactions, such as hydroxylation, epoxidation, Baeyer-Villiger oxidation, and halogenation. These enzymes utilize flavin adenine dinucleotide (FAD) or flavin mononucleotide (FMN) as cofactors to mediate selective incorporation of oxygen…
Int J Biol Macromol. 2026 Apr 1:151728. doi: 10.1016/j.ijbiomac.2026.151728. Online ahead of print. ABSTRACT Cassava (Manihot esculenta Crantz) is a key source of starch, yet conventional extraction methods face significant drawbacks, such as excessive water consumption and low efficiency. This study combined in silico and experimental approaches to optimize cassava starch extraction through ultrasound-assisted enzymatic…
Acc Chem Res. 2026 Apr 3. doi: 10.1021/acs.accounts.5c00763. Online ahead of print. ABSTRACT ConspectusDeveloping systems that can efficiently capture photon energy and convert this energy into fuels and chemicals requires understanding how to assemble molecular components with diverse functions into complete systems possessing selectivity and efficiency in directing charge carriers to catalytic reactions. There are…
Waste Manag. 2026 Apr 1;217:115506. doi: 10.1016/j.wasman.2026.115506. Online ahead of print. ABSTRACT Torrefaction has been proposed as a pre-treatment method for refuse-derived fuel (RDF), enabling the production of carbonized solid fuel (CSF) and improved fuel properties. Yet, the release of volatile organic compounds (VOCs) from the product raises concerns for environmental and occupational safety, especially…
J Colloid Interface Sci. 2026 Mar 30;717:140418. doi: 10.1016/j.jcis.2026.140418. Online ahead of print. ABSTRACT As a renewable resource mainly composed of cellulose, the efficient and high-value utilization of wood has always been a research hotspot. Various biological enzymes play a pivotal role in the natural regeneration process of wood. Inspired by this, this study used…
Bioprocess Biosyst Eng. 2026 Apr 3. doi: 10.1007/s00449-026-03328-4. Online ahead of print. NO ABSTRACT PMID:41931142 | DOI:10.1007/s00449-026-03328-4
ACS Sustain Chem Eng. 2026 Mar 16;14(12):6115-6128. doi: 10.1021/acssuschemeng.5c13384. eCollection 2026 Mar 30. ABSTRACT While biocatalysis in ionic liquids (ILs) using a single enzyme is well known, the successful performance of enzyme cascade reactions (ECRs) using multiple enzymes in ILs is limited by the incompatible stabilization of more than one enzyme in a single IL.…
MedComm (2020). 2026 Mar 19;7(4):e70667. doi: 10.1002/mco2.70667. eCollection 2026 Apr. ABSTRACT Extracellular and membrane proteins serve important roles. They manage cellular communication, structure support, and immune defense. When they malfunction, it cause many diseases like cancer, neurodegeneration, and cardiovascular disorders. Targeted protein degradation (TPD) is a promising therapeutic strategy and aims to remove these faulty…
Trends Biotechnol. 2026 Apr 2:S0167-7799(26)00052-1. doi: 10.1016/j.tibtech.2026.02.013. Online ahead of print. ABSTRACT We present a sustainable microbial platform utilizing gut bacteria and a plant-based medium for stereoselective neurosteroid biosynthesis. Through bioinformatics- and structural biology-guided screening of over 3000 bacterial isolates, we identified three gut strains exhibiting distinct stereospecificities: Holdemania filiformis produces isopregnanolone, Clostridium innocuum generates…
Trends Biotechnol. 2026 Apr 1:S0167-7799(26)00095-8. doi: 10.1016/j.tibtech.2026.03.010. Online ahead of print. ABSTRACT Cofactor engineering is revolutionizing green biomanufacturing by overcoming the fundamental bottleneck between the limited supply/regeneration of cellular energy cofactors [e.g., NAD(P)H, ATP] and the high demands of efficient bioproduction. This review highlights advanced strategies, such as orthogonal systems that separate product synthesis pathways…