Sheng Wu Gong Cheng Xue Bao. 2026 Jun 25;42(6):2454-2468. doi: 10.13345/j.cjb.260184. ABSTRACT At present, in the field of light-driven chemical synthesis, how to achieve efficient and stable solar energy conversion remains a key challenge that needs to be urgently addressed. By mimicking natural photosynthesis, the sustainable production of high-value chemical products and clean fuels using…

Sheng Wu Gong Cheng Xue Bao. 2026 Jun 25;42(6):2555-2565. doi: 10.13345/j.cjb.250913. ABSTRACT As one of the most representative platform compounds, 2,5-furandicarboxylic acid (FDCA) offers significant potential as a renewable alternative to petroleum-derived terephthalic acid, particularly in the field of biodegradable plastics. Traditional thermocatalytic and electrochemical methods for FDCA production face challenges such as poor catalyst…

Sheng Wu Gong Cheng Xue Bao. 2026 Jun 25;42(6):2676-2686. doi: 10.13345/j.cjb.250929. ABSTRACT Efficient asymmetric synthesis of chiral ketones is a significant challenge in green biomanufacturing. To address the scarcity of natural secondary amine enzymes and the insufficient activation capability of existing artificial enzymes towards ketone substrates, this study developed a novel artificial secondary amine enzyme,…

Sheng Wu Gong Cheng Xue Bao. 2026 Jun 25;42(6):2687-2698. doi: 10.13345/j.cjb.260112. ABSTRACT Dihydroavenanthramide D (DHAvD) is an aromatic amide with anti-inflammatory, antipruritic, and antioxidant properties. Its production currently relies on chemical synthesis. Lipases can catalyze the aminolysis of esters or acids to synthesize a series of amide compounds. However, the enzymatic synthesis of DHAvD is…

Org Process Res Dev. 2026 May 28;30(6):1652-1661. doi: 10.1021/acs.oprd.6c00074. eCollection 2026 Jun 19. ABSTRACT Deep eutectic solvents (DESs) can be designed to be enzyme-compatible and substrate solubilizers. Most biocatalytic reactions in DESs are conducted at small scale, and assessing how to scale up DES-based enzymatic reactions is necessary to assess their feasibility and associated challenges.…

Org Process Res Dev. 2026 May 13;30(6):1495-1502. doi: 10.1021/acs.oprd.5c00457. eCollection 2026 Jun 19. ABSTRACT Chiral-substituted carbonyl compounds can be sustainably obtained via asymmetric alkene reduction catalyzed by ene-reductases from the Old Yellow Enzyme (OYE) family. Yet OYEs are seldom implemented in scale-up reactions due to low turnover numbers (TONs). Herein, we demonstrate multigram 150 g/L…

J Phys Chem B. 2026 Jun 25. doi: 10.1021/acs.jpcb.6c01716. Online ahead of print. ABSTRACT The stability and functionality of biomolecules in ionic liquid (IL) environments have garnered significant interest due to their potential applications in biocatalysis, pharmaceutical formulations, and, particularly, protein preservation. In this study, we systematically investigated the effect of three Bmim-based IL-water systems,…

Water Res. 2026 Jun 15;304:126303. doi: 10.1016/j.watres.2026.126303. Online ahead of print. ABSTRACT Toxic organic pollutants (e.g., phenols) and biofouling represent two major threats to aquatic ecosystems. Nanozymes have emerged as promising agents to mitigate these threats, capable of generating effective antibacterial oxidants as well as monitoring and degrading organic pollutants. However, the practical deployment of…

J Food Sci. 2026 Jun;91(6):e71175. doi: 10.1111/1750-3841.71175. ABSTRACT Structured lipids (SLs) have attracted growing industrial interest due to their associated health benefits. Lipases, as highly selective and versatile biocatalysts, are central to the sustainable synthesis of SLs attributed to their ability to operate under mild reaction conditions. However, the limited operational stability of lipases remains…