BioCat Collective
Educating and Building a Broader Biocatalysis Community
Category: Biocatalysis
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Prep Biochem Biotechnol. 2026 Aug 6:1-26. doi: 10.1080/10826068.2026.2690415. Online ahead of print. ABSTRACT Lignin is one of the most abundant yet recalcitrant biopolymers in nature, and its inefficient depolymerization remains a major bottleneck in lignocellulosic biomass valorization and sustainable biorefinery development. Although fungal oxidative enzymes have emerged as promising biocatalysts for lignin degradation, current knowledge…
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Int J Biol Macromol. 2026 Aug 11:153982. doi: 10.1016/j.ijbiomac.2026.153982. Online ahead of print. NO ABSTRACT PMID:42580960 | DOI:10.1016/j.ijbiomac.2026.153982
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J Environ Manage. 2026 Aug 11;415:130682. doi: 10.1016/j.jenvman.2026.130682. Online ahead of print. ABSTRACT Per- and polyfluoroalkyl substances (PFAS) must be treated in large volumes to reach nanogram-per-litre regulatory limits, yet destructive technologies remain confined to the laboratory, while separation methods only concentrate the problem into hazardous waste. This study integrates three functions, enzymatic C-F bond…
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Acta Biomater. 2026 Aug 11:S1742-7061(26)00534-9. doi: 10.1016/j.actbio.2026.08.011. Online ahead of print. ABSTRACT Conventional periodontitis treatments are constrained by challenges such as antibiotic resistance and inadequate tissue regeneration. Herein, we rationally engineer a robust Fe/Mn bimetallic nanozyme (Fe/Mn-Bzyme) derived from a zeolitic imidazolate framework-8 precursor, featuring atomically asymmetric Fe-Mn dual-atom active sites with the Mn1-Fe1-O1-Mn1-N3 coordination…
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J Hazard Mater. 2026 Aug 8;515:143252. doi: 10.1016/j.jhazmat.2026.143252. Online ahead of print. ABSTRACT Polyethylene terephthalate (PET) is a hazardous environmental contaminant that contributes to both plastic and microplastic pollution, with its biodegradation severely limited by the kinetic stability of ester bonds-particularly in alkaline industrial wastewater (pH 9-11) where most known biocatalysts are inactive. To overcome…
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ACS Catal. 2026 Jul 3;16(13):11700-11716. doi: 10.1021/acscatal.6c03394. Epub 2026 Jun 22. ABSTRACT Cobamides are tetrapyrrole cofactors whose core structure, diverse axial ligands, and ability to access distinct redox states underpin the reactivity of a variety of enzymes, including isomerases, methyltransferases, and reductive dehalogenases. These enzymes leverage precise scaffold-controlled interactions to direct radical rearrangement, methyl group…
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Nat Prod Rep. 2026 Aug 11. doi: 10.1039/d6np00031b. Online ahead of print. ABSTRACT Covering: up to 2025Alkaloids constitute an invaluable reservoir for pharmaceutical discovery. However, their therapeutic development has long been constrained by the inefficiencies of plant extraction, as well as the economic impracticality of total chemical synthesis. In recent years, biomanufacturing has emerged as…
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Bioorg Chem. 2026 Aug 10;181:110358. doi: 10.1016/j.bioorg.2026.110358. Online ahead of print. ABSTRACT Heparanase (HPSE) is a promising therapeutic target, yet current heparin-derived inhibitors are limited by structural heterogeneity, poor selectivity, and off-target anticoagulant effects. Here, we synthesized a library of structurally defined heparan sulfate (HS) oligosaccharides via a robust chemoenzymatic strategy, enabling a systematic investigation…
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Prep Biochem Biotechnol. 2026 Aug 6:1-26. doi: 10.1080/10826068.2026.2690415. Online ahead of print. ABSTRACT Lignin is one of the most abundant yet recalcitrant biopolymers in nature, and its inefficient depolymerization remains a major bottleneck in lignocellulosic biomass valorization and sustainable biorefinery development. Although fungal oxidative enzymes have emerged as promising biocatalysts for lignin degradation, current knowledge…
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J Hazard Mater. 2026 Aug 10;515:143227. doi: 10.1016/j.jhazmat.2026.143227. Online ahead of print. ABSTRACT To address the challenge of simultaneously achieving efficient removal, enhanced mineralization, and risk mitigation of dimethyl phthalate (DMP), a multifunctional sodium alginate (SA) microbead platform integrating photocatalysis, enzymatic catalysis, and magnetic recovery was developed. A CeO2@Bi2WO6 heterojunction was first constructed, and the…