BioCat Collective
Educating and Building a Broader Biocatalysis Community
Category: Biocatalysis
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Prep Biochem Biotechnol. 2026 Aug 6:1-26. doi: 10.1080/10826068.2026.2690415. Online ahead of print. ABSTRACT Lignin is one of the most abundant yet recalcitrant biopolymers in nature, and its inefficient depolymerization remains a major bottleneck in lignocellulosic biomass valorization and sustainable biorefinery development. Although fungal oxidative enzymes have emerged as promising biocatalysts for lignin degradation, current knowledge…
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Structure. 2026 Aug 7:S0969-2126(26)00219-4. doi: 10.1016/j.str.2026.07.009. Online ahead of print. ABSTRACT Acetyl-coenzyme A synthetases convert ATP, acetate, and coenzyme A (CoA) into acetyl-CoA, a central metabolite that fuels lipid biosynthesis and regulates protein and RNA acetylation. ACS enzymes contain N- and C-terminal domains that coordinate a two-step ping-pong mechanism involving sequential adenylation and thioester formation…
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Bioresour Technol. 2026 Aug 7:135582. doi: 10.1016/j.biortech.2026.135582. Online ahead of print. ABSTRACT Whole-cell Pickering interfacial biocatalysis effectively overcomes the formidable mass-transfer limitations of hydrophobic substrates in aqueous systems. However, practical implementation is severely hindered by biocatalyst vulnerability under extreme industrial environments and the inherent challenge of post-reaction emulsion separation. Herein, the artificial spore concept is…
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Cell Signal. 2026 Aug 7:112804. doi: 10.1016/j.cellsig.2026.112804. Online ahead of print. ABSTRACT Cancer stem-like cells (CSCs) are believed to be a pivotal contributor to therapy failure in various cancers including osteosarcoma. Targeting CSCs is a promising strategy to overcome chemoresistance and improve outcomes in osteosarcoma treatment. Besides the conventionally studied cytoplasmic p70 ribosomal protein S6…
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Luminescence. 2026 Aug;41(8):e70600. doi: 10.1002/bio.70600. ABSTRACT Zinc oxide nanoparticles (ZnO NPs) were successfully synthesized via an eco-friendly green route using aqueous leaf extract of Sonchus wightianus as a natural reducing and capping agent. UV-Vis spectroscopy revealed a characteristic absorption peak at 267 nm, with a direct optical band gap of 2.96 eV and an Urbach…
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Prep Biochem Biotechnol. 2026 Aug 6:1-26. doi: 10.1080/10826068.2026.2690415. Online ahead of print. ABSTRACT Lignin is one of the most abundant yet recalcitrant biopolymers in nature, and its inefficient depolymerization remains a major bottleneck in lignocellulosic biomass valorization and sustainable biorefinery development. Although fungal oxidative enzymes have emerged as promising biocatalysts for lignin degradation, current knowledge…
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J Biotechnol. 2026 Aug 6:S0168-1656(26)00225-7. doi: 10.1016/j.jbiotec.2026.08.001. Online ahead of print. ABSTRACT In this work, different strategies for the stabilization of commercial Alcalase based on glutaraldehyde modification were investigated. First, the free Alcalase was modified with 0.01, 0.1, or 1% (v/v) glutaraldehyde, which led to a significant increase in thermal stability without loss of enzyme…
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Efficient Antimicrobial Nanoenzymatic Functionalized Hydrogels for Diabetic Infected Wound Treatment
ACS Biomater Sci Eng. 2026 Aug 6. doi: 10.1021/acsbiomaterials.6c00881. Online ahead of print. ABSTRACT The high glycemic environment of diabetic wounds predisposes to bacterial infections that seriously threaten the wound healing process. Therefore, inhibition of bacterial infection and remodeling of the wound microenvironment are crucial for the healing of diabetic infected wounds. In this study,…
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Microbiol Res. 2026 Aug 4;312:128662. doi: 10.1016/j.micres.2026.128662. Online ahead of print. ABSTRACT Root-knot nematodes (RKNs) pose a severe threat to global agricultural production, highlighting the urgent need for effective biocontrol agents. However, the mechanisms by which biocontrol agents suppress RKNs in complex soil environments remain poorly understood, which hinders the development and practical application of…
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Pest Manag Sci. 2026 Aug 5. doi: 10.1002/ps.71189. Online ahead of print. ABSTRACT BACKGROUND: The ladybird Harmonia axyridis is an important predatory natural enemy, and during both predation and oviposition it encounters interference from the black garden ant Lasius niger, as ants aggressively defend aphid colonies and thereby restrict ladybirds’ access to suitable foraging and…