BioCat Collective
Educating and Building a Broader Biocatalysis Community
Category: Biocatalysis
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World J Microbiol Biotechnol. 2026 Aug 14;42(9):467. doi: 10.1007/s11274-026-05188-2. ABSTRACT Lignocellulosic biomass represents a promising renewable feedstock for second-generation (2G) bioethanol production; however, the recalcitrant nature of lignin remains a major barrier to efficient biomass conversion. The present study investigated the application of for enhanced lignin-targeted pretreatment followed by enzymatic hydrolysis and bioethanol production Among…
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Chembiochem. 2026 Aug 14;27(15):e70497. doi: 10.1002/cbic.70497. ABSTRACT Formate dehydrogenases represent a highly attractive tool for nicotinamide cofactor regeneration to drive biocatalytic reductions and oxygenations by NADH-dependent oxidoreductases with formate as a cheap, atom-economic terminal reductant. However, despite the clear benefits over other recycling systems, native FDHs remain rather unpopular, mainly due to their intrinsic, low…
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Nucleic Acids Res. 2026 Aug 10;54(15):gkag710. doi: 10.1093/nar/gkag710. ABSTRACT A widely adopted modification of CRISPR-Cas9 is fusion of the naturally occurring two-component dual guide RNA (dgRNA) to create an artificial single guide RNA (sgRNA). Here we find that these guide architectures induce differential catalysis, gene editing, and specificity. Spacer sequence and RNA structural features could…
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Carbohydr Res. 2026 Aug 6;569:110060. doi: 10.1016/j.carres.2026.110060. Online ahead of print. ABSTRACT This review characterizes the mechanisms of action of animal polysaccharides (chitin, chitosan, hyaluronan, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparin/heparan sulfate) based on their structural and conformational features. A systematic search was conducted in PubMed, Scopus, Web of Science, and the Russian Citation…
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Prep Biochem Biotechnol. 2026 Aug 6:1-26. doi: 10.1080/10826068.2026.2690415. Online ahead of print. ABSTRACT Lignin is one of the most abundant yet recalcitrant biopolymers in nature, and its inefficient depolymerization remains a major bottleneck in lignocellulosic biomass valorization and sustainable biorefinery development. Although fungal oxidative enzymes have emerged as promising biocatalysts for lignin degradation, current knowledge…
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Adv Sci (Weinh). 2026 Aug 13:e77136. doi: 10.1002/advs.77136. Online ahead of print. ABSTRACT Whole-cell catalysis holds great potential in the production of rare ginsenoside compound K (CK), but it is limited by poor mass transfer and inadequate stability in practice. Herein, we report a scalable whole-cell immobilization platform through in situ assembly of recombinant Escherichia…
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Molecules. 2026 Jul 28;31(15):2626. doi: 10.3390/molecules31152626. ABSTRACT The chronic overuse of antibiotics has accelerated the emergence of antibiotic-resistant bacteria, creating a global public health crisis as conventional therapies fail against multidrug-resistant pathogens spreading through water and food chains. Cadmium sulfide (CdS) has been established as an important visible-light-driven photocatalyst for antibacterial applications. This brief review…
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ACS Appl Mater Interfaces. 2026 Aug 12;18(31):43194-43201. doi: 10.1021/acsami.6c11681. ABSTRACT Enzyme therapeutics operating in harsh physiological microenvironments are inherently constrained by rapid unfolding, proteolytic degradation, and acid-induced deactivation, especially in stomachs. These vulnerabilities severely limit catalytic longevity and practical efficacy, particularly for acetaldehyde detoxification in humans. Achieving durable enzymatic function in such hostile conditions requires…
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Foods. 2026 Aug 3;15(15):2724. doi: 10.3390/foods15152724. ABSTRACT Argan oil (Argania spinosa L.) is a culturally and economically significant product in North Africa, yet little is known about how extraction practices shape its nutritional and sensory qualities. The present study compares mechanical cold pressing with solvent extraction (diethyl ether and petroleum ether) on roasted and unroasted…
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Molecules. 2026 Jul 24;31(15):2584. doi: 10.3390/molecules31152584. ABSTRACT Coumarins are compounds that are naturally found in various plants and are known for their potential pharmacological characteristics, such as anti-inflammatory, antibacterial, antiparasitic, and anticoagulant activities. Despite the potential pharmacological properties, structural modification of coumarins is important to enhance the biological activity, solubility, bioavailability, and various therapeutic characteristics.…