JACS Au. 2026 Aug 3;6(8):4380-4395. doi: 10.1021/jacsau.6c01015. eCollection 2026 Aug 24. ABSTRACT Transitioning catalysis from batch to continuous flow remains a key objective of sustainable chemistry, yet the effective retention of homogeneous catalysts and enzymes under flow conditions is a persistent challenge. This Perspective highlights Pickering emulsion droplet (PED)-based fixed-bed reactors as a modular strategy…

Foods. 2026 Aug 20;15(16):2914. doi: 10.3390/foods15162914. ABSTRACT Stearidonic acid (SDA) and γ-linolenic acid (GLA) are recognized for their anti-inflammatory and cardiometabolic benefits, yet their natural dietary sources remain scarce. This study aimed to develop and optimize the enzymatic synthesis of lysophosphatidylcholine (LPC) enriched with GLA and SDA in a solvent-free system using Echium plantagineum seed…

Biomolecules. 2026 Aug 1;16(8):1124. doi: 10.3390/biom16081124. ABSTRACT Carcinine is an imidazole dipeptide with potent antioxidant and antiglycation properties, although its chemical synthesis currently relies on severely environmentally harmful processes. In this work, a multi-enzyme cascade biotransformation system comprising 4′-phosphopantetheinyl transferase and non-ribosomal peptide synthetase was constructed. To overcome the limitations arising from stochastic spatial distribution…

Biology (Basel). 2026 Aug 20;15(16):1437. doi: 10.3390/biology15161437. ABSTRACT Cuticular wax is a critical component of the plant cuticle, playing an indispensable role in plant growth, development, and defense against environmental stresses. ECERIFERUM3 (CER3), a very-long-chain fatty acyl-CoA reductase, serves as a pivotal hub channeling carbon resources into the alkane- and alcohol-forming pathways respectively. Here, we…

Int J Mol Sci. 2026 Aug 8;27(16):7125. doi: 10.3390/ijms27167125. ABSTRACT The global oil-processing industry generates substantial quantities of by-products and secondary streams, including oilseed cakes, pomaces, hulls, and wastewaters, which remain largely underutilized despite being rich sources of high-value bioactive compounds. The development of sustainable strategies for the valorization of these residues is increasingly recognized…

Int J Mol Sci. 2026 Aug 20;27(16):7463. doi: 10.3390/ijms27167463. ABSTRACT 4′-Hydroxymethoxychalcones represent structurally diverse chalcone derivatives that are attractive substrates for microbial functionalization; however, the impact of methoxy substitution position on their cascade biotransformation by fungi remains poorly understood. In this study, three regioisomeric 4′-hydroxymethoxychalcones, featuring ortho-, meta-, or para-methoxy groups on ring B, were…

Int J Mol Sci. 2026 Aug 21;27(16):7492. doi: 10.3390/ijms27167492. ABSTRACT A hard protein corona was engineered onto tannic acid-modified magnetic nanoparticles (SAMN@TA), a magnetic and luminescent core-shell nano-carrier, using bovine serum amine oxidase (BSAO), an enzyme catalyzing the oxidation of polyamines and producing the corresponding aldehydes and hydrogen peroxide. The absorption and intracellular bioactivity of…

Molecules. 2026 Aug 13;31(16):2821. doi: 10.3390/molecules31162821. ABSTRACT Starch-modifying glycoside hydrolases (GHs) typically operate via a retaining double-displacement mechanism, involving formation of a covalent glycosyl-enzyme intermediate. This intermediate can be resolved either by water, resulting in hydrolysis, or by a glucan acceptor, leading to transglucosylation. Many GHs exhibit both catalytic activities, although they are classified according…