ACS Nano. 2026 Aug 25;20(33):23564-23582. doi: 10.1021/acsnano.6c12587. ABSTRACT The sustainable recycling of spent lithium iron phosphate (LiFePO4) batteries via bioleaching is critically important yet often constrained by low processing capacity and severe microbial oxidative stress. Herein, we report a highly efficient biocatalytic strategy utilizing Gluconobacter oxydans as a whole-cell biocatalyst for the leaching of spent…

Langmuir. 2026 Aug 25;42(33):24455-24465. doi: 10.1021/acs.langmuir.6c03409. ABSTRACT Pickering interfacial catalysis in Pickering emulsions offers a promising platform for heterogeneous catalytic reactions. In the present work, immobilized matrixes with tunable hydrophobicity were fabricated by grafting hydrophilic silica particles with different amounts of octadecyltrichlorosilane (ODTs). By screening the activity of corresponding immobilized lipases, hyperperformance, characterized by both…

Integr Biol (Camb). 2026 Jan 16;18:zyag018. doi: 10.1093/intbio/zyag018. ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a critical threat in healthcare and community settings. Meanwhile, the effectiveness of treatment is limited by vancomycin, which remains the only frontline drug against MRSA. The emergence of new strains of MRSA, along with the development of vancomycin-resistant S. aureus…

Chembiochem. 2026 Sep 14;27(17):e70519. doi: 10.1002/cbic.70519. ABSTRACT Carbonic anhydrase is among the fastest known enzymes, yet its performance after immobilization remains difficult to rationalize. Conventional immobilization design emphasizes stability, enzyme loading, and mass transfer while largely neglecting proton transport. In soluble carbonic anhydrase, proton transfer can limit catalytic turnover under defined pH and buffer conditions.…

Probiotics Antimicrob Proteins. 2026 Aug 31. doi: 10.1007/s12602-026-11194-5. Online ahead of print. ABSTRACT Given the similarities of action mechanism between amyloidogenic peptides (e.g. Aβ) and antimicrobial peptides (AMPs), we rationally engineered an amyloidogenic Aβ peptide to improve its antimicrobial activity: the aggregation-prone fragment was reverse-repeated to increase antimicrobial activity; poly-arginine (R) was flanked to both…

Chembiochem. 2026 Sep 14;27(17):e70492. doi: 10.1002/cbic.70492. ABSTRACT Biocascade catalysis has emerged as a defining paradigm in contemporary synthesis, enabling the orchestration of multiple enzymatic transformations within a single vessel. By allowing intermediates to flow seamlessly between successive steps without isolation, cascades emulate the elegance of natural biosynthetic networks while delivering significant gains in atom economy…

ChemSusChem. 2026 Sep 14;19(17):e71032. doi: 10.1002/cssc.71032. ABSTRACT Engineered microbial systems offer a route for converting lignin into value-added aromatics, yet lignin-derived intermediates are cytotoxic and suppress growth and metabolic flux. Here, we show that ectoine, a compatible solute, mitigates lignin-induced stress in Halalkalibacterium ligniniphilum L1 and improves bioconversion performance. At 0.1 g L-1, ectoine alleviated…

ACS Appl Mater Interfaces. 2026 Aug 24. doi: 10.1021/acsami.6c14150. Online ahead of print. ABSTRACT Metal-organic frameworks (MOFs), owing to their exceptional porosity and tunable chemical functionality, have emerged as leading platforms for enzyme immobilization. The nature and magnitude of interfacial interactions between enzymes and MOF carriers fundamentally govern the conformational integrity, substrate accessibility, and catalytic…

Bioorg Chem. 2026 Aug 28;181:110448. doi: 10.1016/j.bioorg.2026.110448. Online ahead of print. ABSTRACT Glycosylation commonly inactivates macrolide antibiotics, and the resulting glycosides are largely dismissed as inactive waste products. Whether such molecules retain hidden therapeutic potential remains underexplored. Here, we address this question using spiramycin I 2′-O-glucopyranoside as a proof-of-concept model. The glycoside was enzymatically synthesized…

Enzyme Microb Technol. 2026 Aug 27;202:110960. doi: 10.1016/j.enzmictec.2026.110960. Online ahead of print. ABSTRACT Hydrogen peroxide (H2O2) is a key green oxidant for industrial biotransformations, yet its conventional production, storage, and handling present significant safety, logistical, and sustainability challenges. Enzymatic in situ generation using oxidases has emerged as an attractive alternative, enabling controlled H2O2 supply, eliminating…