Enzyme Microb Technol. 2026 Jul 7;200:110932. doi: 10.1016/j.enzmictec.2026.110932. Online ahead of print. ABSTRACT The application of steam-exploded green coconut fiber (GCF) (an agro-industrial waste) was studied as a support for the immobilization of lipases, using lipase B from Candida antarctica (CALB), lipase from Pseudomonas fluorescens (PFL) or the engineered lipase Eversa (EL) as model enzymes.…

Nature. 2026 Jul 8. doi: 10.1038/s41586-026-10744-9. Online ahead of print. ABSTRACT Methanogens are central to global carbon cycling and among the largest biological sources of methane, a potent greenhouse gas1. At the heart of their energy metabolism lies the Hdr-Vhu-Fwd super-assembly, which couples H2 oxidation with CO2 reduction through flavin-based electron bifurcation. Here we present…

Plant Cell Physiol. 2026 Jul 8:pcag095. doi: 10.1093/pcp/pcag095. Online ahead of print. ABSTRACT The plant extracellular space, including the cell wall, is a dynamic signaling compartment outside the plasma membrane that plays crucial roles in cell-cell communication and developmental coordination. Although early embryogenesis is known to be orchestrated by both intracellular and extracellular cues, the…

Nat Prod Rep. 2026 Jul 8. doi: 10.1039/d6np00049e. Online ahead of print. ABSTRACT Coverage of selected chemoenzymatic natural product syntheses reported in the period 2021-2025Chemoenzymatic synthesis has emerged as a powerful strategy for the efficient construction and diversification of complex natural products by integrating the selectivity of biocatalysis with the flexibility of synthetic chemistry. This…

Nat Commun. 2026 Jul 7. doi: 10.1038/s41467-026-75314-z. Online ahead of print. ABSTRACT Enzyme immobilization is pivotal to sustainable biocatalysis, yet the most widespread protocol of physical adsorption on static porous supports suffers from enzyme leakage and short catalytic lifespan. We introduce a dynamic-pore mechano-locking strategy employing tetrafluoroazobenzene-engineered covalent organic frameworks (COFs), where visible-light-mediated isomerization enables…

Int J Biol Macromol. 2026 Jul 7:153396. doi: 10.1016/j.ijbiomac.2026.153396. Online ahead of print. ABSTRACT The anthocyanin biosynthetic pathway (ABP), a branch of the phenylpropanoid pathway, is responsible for the production of a wide range of flavonoid compounds in plants. Anthocyanin-related glutathione transferases (arGSTs) have long been proposed to act as non-catalytic carrier proteins, mediating the…

Chembiochem. 2026 Jul 14;27(13):e70459. doi: 10.1002/cbic.70459. ABSTRACT The aminohexanoate oligomer hydrolase enzymes, NylCs, have emerged as lead biocatalysts for their potential to depolymerize nylon in a bioremediation context. Protein engineering efforts have thus far improved thermostability and activity, but conversion of the polymer to smaller oligomers remains low. With the intent to accelerate engineering efforts,…

Angew Chem Int Ed Engl. 2026 Jul 7:e1402106. doi: 10.1002/anie.1402106. Online ahead of print. ABSTRACT gem-Difluorophosphonates are pivotal structural motifs in pharmaceuticals and bioactive molecules. While photoenzymatic catalysis provides a powerful platform to overcome the challenges of enantioselective synthesis, engineering enzymes for non-natural transformations remains an arduous, labor-intensive process. Although predictive methods utilizing protein language…