Educating and Building a Broader Biocatalysis Community
J Microbiol Biotechnol. 2026 Jul 23;36:e2607018. doi: 10.4014/jmb.2607.07018. ABSTRACT Microbial biocatalysis spans biological platforms ranging from purified enzymes and multienzyme assemblies to electroenzymatic systems, whole-cell biocatalysts, and genetically programmable microbial cell factories. Yet despite their biological diversity, functional biocatalytic performance is often influenced by both catalytic activity and molecular accessibility. This recurring constraint highlights molecular…
Microb Biotechnol. 2026 Aug;19(8):e70420. doi: 10.1111/1751-7915.70420. ABSTRACT Plastics have become indispensable to modern society, but their predominantly linear production and end-of-life management are increasingly incompatible with environmental and resource constraints. Biotechnology offers new opportunities to reshape this system, not only by enabling the biological recycling and upcycling of conventional plastics, but also by supporting the…
Org Biomol Chem. 2026 Jul 28. doi: 10.1039/d6ob00602g. Online ahead of print. ABSTRACT The application of biocatalysis in pharmaceutical synthesis has grown in an attempt to improve the sustainability and greenness of production processes. To meet the demands of practical applications, biocatalysts with superior action, specificity, thermal stability, and solvent tolerance are in great demand.…
Adv Mater. 2026 Jul 28:e74319. doi: 10.1002/adma.74319. Online ahead of print. ABSTRACT PANoptosis has emerged as a compelling strategy to potentiate antitumor immune responses. However, achieving specific PANoptotic cancer-cell death while sparing normal tissues remains a central challenge, as current strategies are constrained by inadequate spatiotemporal controllability and insufficient generation of key effector species, particularly…
J Physiol. 2026 Jul 28. doi: 10.1113/JP290658. Online ahead of print. ABSTRACT Fibroblasts have emerged as inflammatory entities in ulcerative colitis (UC) and eosinophilic oesophagitis, positioning these cells as attractive therapeutic targets. Previous studies have shown that hydroxylase inhibitors elicit anti-inflammatory responses, but their effects on fibroblasts during inflammation remain unknown. Here we test the…
Int J Mol Sci. 2026 Jul 11;27(14):6210. doi: 10.3390/ijms27146210. ABSTRACT Non-aeruginosa Pseudomonas (NAP) species represent a diverse and ubiquitous group of Gram-negative bacteria inhabiting a wide range of environmental niches, from soil and water to plant rhizospheres and clinical settings. While Pseudomonas aeruginosa has historically dominated clinical and research focus, the significance of NAP species,…
Biomedicines. 2026 Jun 25;14(7):1444. doi: 10.3390/biomedicines14071444. ABSTRACT Background/Objectives: The corpus luteum (CL) in the dog is the sole source of progesterone (P4) during diestrus and pregnancy, making it a key regulator of reproductive function. However, robust and functionally validated in vitro models of canine luteal cells remain limited. This study aimed to establish and characterize…
Molecules. 2026 Jul 8;31(14):2403. doi: 10.3390/molecules31142403. ABSTRACT In this study, we characterized the chemical composition of lime essential oil (Citrus aurantifolia) by GC-MS and evaluated the effects of lime essential oil and its major constituent, (R)-(+)-limonene, on rumen fermentation, methane production, microbial community structure and metabolic responses in dairy cows. In vitro assays were used…
Molecules. 2026 Jul 16;31(14):2487. doi: 10.3390/molecules31142487. ABSTRACT Metabolic syndrome (MetS) is a major driver of cardiovascular disease, renal injury, and hepatic steatosis, largely through chronic low-grade inflammation and oxidative stress. This study evaluated the cardioprotective, nephroprotective, and hepatoprotective potential of a polyphenol-rich fraction (PP) isolated from Ilex aquifolium leaves in obese Zucker (fa/fa) rats-a well-established…
Microorganisms. 2026 Jul 13;14(7):1524. doi: 10.3390/microorganisms14071524. ABSTRACT The growing demand for sustainable agricultural inputs has encouraged the development of biotechnological alternatives based on microbe-derived enzymes and bioactive metabolites. In this study, co-fermentation strategies involving different Trichoderma strains were investigated as a process-based approach to enhance the production of enzymes and plant growth-promoting metabolites with agricultural…