Educating and Building a Broader Biocatalysis Community
Food Chem. 2026 Jul 29;525(Pt 3):150588. doi: 10.1016/j.foodchem.2026.150588. Online ahead of print. ABSTRACT Six agri-food side streams, linseed press cake (LPC), brewer’s spent grains (BSG), bread residues (BR), apple pomace (AP), sugar beet pulp (SBP), and acid cheese whey (CW), were compared as feedstocks for compound-resolved Monascus ruber SRZ112-m22 pigment production under submerged (SmF) and…
RSC Adv. 2026 Jul 31. doi: 10.1039/d6ra03766f. Online ahead of print. ABSTRACT NADPH-dependent biocatalysis is widely used for the synthesis of valuable chemicals, and maintaining an effective NADPH pool during catalysis is critical for its performance. Although cofactor regeneration has been extensively studied, the maintenance of the NADPH pool in complex biocatalytic environments, such as…
Food Chem. 2026 Jul 27;525(Pt 3):150589. doi: 10.1016/j.foodchem.2026.150589. Online ahead of print. ABSTRACT This study presents a food-grade, multi-chamber W/O/W high internal phase Pickering emulsion (HIPPE) system for interfacial catalysis, which stabilized by a zein nanoparticle (ZNP)-lipase complex crosslinked with tannic acid (TA). Experiments and molecular dynamics simulations confirmed that the cross-linking between TA, ZNPs,…
Bioresour Technol. 2026 Jul 31:135530. doi: 10.1016/j.biortech.2026.135530. Online ahead of print. ABSTRACT Polybutylene adipate terephthalate (PBAT) is prone to incomplete degradation, leading to environmental pollution and carbon resource waste. Biodegradation and valorization of waste plastics are essential for addressing plastic pollution and promoting a circular economy. Enzymatic degradation offers advantages, but free enzymes suffer from…
IMA Fungus. 2026 Jul 22;17:e181825. doi: 10.3897/imafungus.17.181825. eCollection 2026. ABSTRACT Gongronella, a genus within the Mucoromycota, exhibits remarkable ecological adaptability and is widely distributed across diverse habitats. Recent research has revealed its capacity to colonize plant roots, stimulate plant growth, and enhance nutrient acquisition, underscoring its potential as both a biofertilizer and a biocontrol agent.…
J Am Chem Soc. 2026 Jul 29;148(29):31120-31129. doi: 10.1021/jacs.6c06951. ABSTRACT Most conventional alkene synthesis reactions (e.g., elimination et al.) inherently favor the formation of thermodynamically more stable E-isomers, posing a long-standing challenge for direct access to Z-alkenes. Here, we report the reprogramming of a thiamine diphosphate (ThDP)-dependent enzyme to catalyze a formal dehalogenative elimination that…
Science. 2026 Jul 30;393(6810):aef5438. doi: 10.1126/science.aef5438. Epub 2026 Jul 30. ABSTRACT Lignans constitute a diverse family of plant metabolites with therapeutic potential. Among them, podophyllotoxin-type aryltetralin lignans serve as precursors for etoposide and teniposide. Etoposide is an essential anticancer medicine approved for first-line treatment of small cell lung cancer, whereas teniposide is used for treatment…
Chembiochem. 2026 Aug 14;27(15):e70487. doi: 10.1002/cbic.70487. ABSTRACT In the search for more efficient chemical processes to valorize renewable feedstocks, oleate hydratases (Ohys) represent promising biocatalysts. These enzymes can convert cis-Δ9 fatty acids like oleic acid into their hydroxy fatty acid counterparts using only water as co-reagent and with unparallelled selectivity. A multitude of Ohys has…
Food Sci Nutr. 2026 Jul 28;14(8):e72140. doi: 10.1002/fsn3.72140. eCollection 2026 Aug. ABSTRACT Obesity is a global health crisis driven by complex metabolic dysregulation. Although Akkermansia muciniphila (AKK) has emerged as a promising next-generation probiotic for metabolic health, its synergistic potential with natural anti-obesity compounds remains largely unexplored. Here, we evaluated the combined administration of pasteurized…
JACS Au. 2026 Jun 11;6(7):4073-4084. doi: 10.1021/jacsau.6c00594. eCollection 2026 Jul 27. ABSTRACT The profound stability of bacterial spores makes them a promising platform for biotechnological applications like biocatalysis, bioremediation, drug delivery, etc. However, though the Bacillus subtilis spore is composed of >40 types of proteins, only ∼12 have been explored as fusion carriers for protein…