BioCat Collective
Educating and Building a Broader Biocatalysis Community
Category: Biocatalysis
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J Inorg Biochem. 2026 Sep 9;286:113454. doi: 10.1016/j.jinorgbio.2026.113454. Online ahead of print. ABSTRACT Responsive MRI probes are a powerful platform for the non-invasive detection of enzymatic activity in biological tissues. Herein, two series of DO3A-based molecular probes, LnL1 and LnL2 (Ln = Gd3+, Tb3+ and Tm3+), capable of responding to enzyme tyrosinase (TYR), were designed…
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RSC Chem Biol. 2026 Sep 7. doi: 10.1039/d6cb00217j. Online ahead of print. ABSTRACT Herein we report a divergent route from a single diazido precursor to four 6-deoxy-l-altdiamides, converted on preparative scale by promiscuous C. jejuni PseI into pseudaminic acid derivatives Pse5Ac7Ac, Pse5Ac7Fm, Pse5Ac7Hb and Pse5Hb7Fm. Surface plasmon resonance revealed the 1E8 monoclonal antibody tolerates varied…
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RSC Adv. 2026 Sep 15. doi: 10.1039/d6ra06805g. Online ahead of print. ABSTRACT Indigo carmine (IC) persists in aquatic environments due to its high solubility, aromatic stability, and sulfonated structure, raising toxicity concerns and inducing the formation of harmful oxidative intermediates. This review critically summarizes the information on IC and provides a mechanistic evaluation of its…
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Appl Environ Microbiol. 2026 Sep 16:e0149026. doi: 10.1128/aem.01490-26. Online ahead of print. ABSTRACT This study presents the discovery and characterization of a novel thermophilic 3-quinuclidinone reductase (ScQR) identified through metagenomic mining of hot spring environments. ScQR, a member of the short-chain dehydrogenase/reductase (SDR) superfamily, was heterologously expressed in Escherichia coli, and its catalytic properties were…
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RSC Adv. 2026 Sep 15. doi: 10.1039/d6ra04035g. Online ahead of print. ABSTRACT Bamboo-derived biochars obtained via fast and slow pyrolysis conditions were used as supports for the immobilization of Candida antarctica lipase B (CALB) through physical adsorption. The FP- and SP-based materials were then evaluated in esterification and hydrolysis reactions under both batch and continuous-flow…
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Compr Rev Food Sci Food Saf. 2026 Sep;25(5):e70656. doi: 10.1111/1541-4337.70656. ABSTRACT Amylosucrase (ASase, E.C. 2.4.1.4) is a transglucosidase that catalyzes α-glucan synthesis and transglycosylation reactions using sucrose as the sole substrate. Unlike Leloir glycosyltransferases requiring expensive nucleotide sugars, ASases utilize readily available sucrose as a cost-effective glucose donor, offering economic advantages for industrial applications. This…
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Small. 2026 Sep 16:e75811. doi: 10.1002/smll.75811. Online ahead of print. ABSTRACT The rational design of bioactive molecules to precisely engineer the energy-conversion interfaces represents an unexplored frontier in advanced therapeutics. Herein, we report a curcumin (Cur)-adapted nano-composites (BiO2-X/Cur), integrated into a dissolvable microneedles (MNs) patch, for synergistic piezo-sono-thermal therapy against drug-resistant skin infections. The natural…
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Angew Chem Int Ed Engl. 2026 Sep 15:e2218878. doi: 10.1002/anie.2218878. Online ahead of print. ABSTRACT N- and O-glycosylations are essential post-translational modifications involved in numerous physiological and pathological processes. Sulfated N- and O-glycans, commonly found on biologically important glycoproteins, serve as critical mediators of molecular recognition. However, their precise structure-function relationships remain poorly understood, primarily…
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Crit Rev Biotechnol. 2026 Sep 15:1-16. doi: 10.1080/07388551.2026.2728042. Online ahead of print. ABSTRACT Microbial cell surface display systems represent a promising and robust approach for engineering whole-cell biocatalysts, with broad applications in biotechnology and biomedicine. This methodology overcomes limitations in substrate transport, eliminates the laborious and time-consuming process of enzyme purification, and enhances reusability and…
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Biotechnol Appl Biochem. 2026 Sep 15. doi: 10.1002/bab.70208. Online ahead of print. ABSTRACT Ferulic acid esterases (FAEs) are enzymes that interact with esterified components of plant cell walls, facilitating the release of free ferulic acid (FA) from plant materials. Therefore, they hold significant importance across multiple industries, including pharma, food, and cosmetics. This investigation involved…