ACS Appl Mater Interfaces. 2026 Sep 14. doi: 10.1021/acsami.6c12503. Online ahead of print. ABSTRACT A cytochrome P450-mimetic monodispersed Fe-porphyrin-based porous framework is designed and synthesized via a FeCl3-assisted Friedel-Crafts reaction, to combine the advantages of heterogeneous systems with enzymatic reactivity. Specifically, the Fe-porphyrin site in this material mimics the heme-center in cytochrome P450, which efficiently…

ACS Appl Mater Interfaces. 2026 Sep 14. doi: 10.1021/acsami.6c12503. Online ahead of print. ABSTRACT A cytochrome P450-mimetic monodispersed Fe-porphyrin-based porous framework is designed and synthesized via a FeCl3-assisted Friedel-Crafts reaction, to combine the advantages of heterogeneous systems with enzymatic reactivity. Specifically, the Fe-porphyrin site in this material mimics the heme-center in cytochrome P450, which efficiently…

ACS Appl Mater Interfaces. 2026 Sep 14. doi: 10.1021/acsami.6c12503. Online ahead of print. ABSTRACT A cytochrome P450-mimetic monodispersed Fe-porphyrin-based porous framework is designed and synthesized via a FeCl3-assisted Friedel-Crafts reaction, to combine the advantages of heterogeneous systems with enzymatic reactivity. Specifically, the Fe-porphyrin site in this material mimics the heme-center in cytochrome P450, which efficiently…

J Am Chem Soc. 2026 Sep 9;148(35):38519-38529. doi: 10.1021/jacs.6c15193. ABSTRACT As Brønsted acid sites (BASs) serve as the active centers in zeolite-catalyzed reactions, comprehending their precise location, population, and dynamic behavior is crucial for catalyst optimization─yet their characterization remains a significant challenge. Here, we demonstrate that 29Si NMR exhibits high environmental sensitivity in silicoaluminophosphate molecular…

Angew Chem Int Ed Engl. 2026 Sep 8:e2349367. doi: 10.1002/anie.2349367. Online ahead of print. ABSTRACT Enantioselective C(sp3)─H functionalization reactions are appealing synthetic organic chemistry tools to streamline access to valuable chiral molecules from simple precursors. Chiral piperidines are ubiquitous motifs in pharmaceuticals and natural products, yet methods for their preparation from simple non-chiral precursors remain…

Angew Chem Int Ed Engl. 2026 Sep 7:e9907362. doi: 10.1002/anie.9907362. Online ahead of print. ABSTRACT Polyolefin hydrogenolysis offers a promising route for the upcycling of plastic waste, yet is hindered by the high cost of noble-metal catalysts and the safety concerns of high-pressure H2. Current systems typically rely on Ru or Pt catalysts to mediate…

Angew Chem Int Ed Engl. 2026 Sep 4:e6571996. doi: 10.1002/anie.6571996. Online ahead of print. ABSTRACT Precious metal nanoparticles generally aggregate through Ostwald ripening in the absence of anchoring sites, whereas in the presence of suitable coordination environments, they can disperse into thermodynamically stable single-atom (SA) with chelate structures. Herein, an unexpected staggered transformation between nanoparticles…

Small. 2026 Sep 3:e75628. doi: 10.1002/smll.75628. Online ahead of print. ABSTRACT Inspired by the electron-transfer function of biological ferredoxins, we report a biomimetic iron-sulfur cluster-functionalized porous organic polymer (FeS-POP) for efficient oxygen evolution reaction (OER). FeS-POP is constructed through polymerization-induced restructuring of a diamagnetic diiron carbonyl precursor (FeS-Com), wherein Fe─Fe bond cleavage and decarbonylation trigger…

Carbohydr Polym. 2026 Oct 15;390:125786. doi: 10.1016/j.carbpol.2026.125786. Epub 2026 Aug 24. ABSTRACT Polysaccharide-based physical hydrogels are promising drug-delivery platforms due to their biocompatibility, tunable mechanical properties, and reversible crosslinking. However, bulk hydrogels may require in situ gelation for administration, while controlled release of nanoparticles larger than the hydrogel mesh remains challenging. This study aimed to…

Carbohydr Polym. 2026 Oct 15;390:125727. doi: 10.1016/j.carbpol.2026.125727. Epub 2026 Aug 4. ABSTRACT Engineering cyclodextrin-based materials enabling real-time diagnosis and on-demand therapy is highly desirable for hyperuricemia and gout management. Here, we design a novel cyclodextrin-engineered bioinspired nanozyme (T-CD/Pt), and integrate it into a bi-regional microneedle (TP-MNs). Coupled with a biowaste-derived coffee ground photothermal film (CPS-F),…