Nat Commun. 2026 Jul 10;17(1):6081. doi: 10.1038/s41467-026-74903-2. ABSTRACT Oxygenic photosynthesis generates ATP and NADPH via linear electron flow from water to NADP+, a process thought to require photosystem I (PSI) for reductant formation. Here we demonstrate that oxygenic photosynthesis can operate without PSI in the cyanobacterium Synechocystis sp. PCC 6803. Using genetic engineering and adaptive…

Commun Chem. 2026 Jul 9;9(1):240. doi: 10.1038/s42004-026-02128-x. ABSTRACT α-Tertiary amino acids (ATAAs), featuring a fully substituted α-carbon bearing two carbon substituents, are valuable building blocks in natural products, pharmaceuticals, and agrochemicals, yet their stereoselective synthesis remains a longstanding challenge in conventional chemical synthesis. Recent advances in enzymatic catalysis have provided efficient and sustainable solutions for…

J Am Chem Soc. 2026 Jul 8. doi: 10.1021/jacs.6c07143. Online ahead of print. ABSTRACT Fatty acid photodecarboxylase (FAP) is a photoenzyme that converts fatty acids into hydrocarbons through light-driven radical chemistry. Although the early photochemical steps have been elucidated, the molecular mechanism governing the catalytic termination remains unresolved. Here, we address this issue through a…

J Am Chem Soc. 2026 Jul 8. doi: 10.1021/jacs.6c07143. Online ahead of print. ABSTRACT Fatty acid photodecarboxylase (FAP) is a photoenzyme that converts fatty acids into hydrocarbons through light-driven radical chemistry. Although the early photochemical steps have been elucidated, the molecular mechanism governing the catalytic termination remains unresolved. Here, we address this issue through a…

J Am Chem Soc. 2026 Jul 8. doi: 10.1021/jacs.6c07143. Online ahead of print. ABSTRACT Fatty acid photodecarboxylase (FAP) is a photoenzyme that converts fatty acids into hydrocarbons through light-driven radical chemistry. Although the early photochemical steps have been elucidated, the molecular mechanism governing the catalytic termination remains unresolved. Here, we address this issue through a…

J Am Chem Soc. 2026 Jul 8. doi: 10.1021/jacs.6c07143. Online ahead of print. ABSTRACT Fatty acid photodecarboxylase (FAP) is a photoenzyme that converts fatty acids into hydrocarbons through light-driven radical chemistry. Although the early photochemical steps have been elucidated, the molecular mechanism governing the catalytic termination remains unresolved. Here, we address this issue through a…

N Biotechnol. 2026 Jul 2:S1871-6784(26)00085-3. doi: 10.1016/j.nbt.2026.06.010. Online ahead of print. ABSTRACT A major challenge in developing effective photocatalysts lies in engineering the efficient coupling of one-electron photochemistry with the multi-electron requirements of chemical transformations. Here we demonstrate biohybrid assemblies that achieve this key performance requirement by storing photoenergized electrons on multiple heme cofactors within…

Front Chem. 2026 Jun 16;14:1878757. doi: 10.3389/fchem.2026.1878757. eCollection 2026. ABSTRACT Conventional nanozymes still suffer from limited catalytic efficiency and poor substrate selectivity, which impede their clinical translation. Recently, photo-responsive nanozymes have emerged as a promising platform for precision biomedicine by integrating photocatalytic processes with enzyme-mimetic catalysis, enabling spatiotemporally controlled enhancement of catalytic activity. In this…

Colloids Surf B Biointerfaces. 2026 Jun 21;267:115923. doi: 10.1016/j.colsurfb.2026.115923. Online ahead of print. ABSTRACT Burn wounds infected with Staphylococcus aureus (S. aureus) are often characterized by excessive early inflammation, which leads to persistent oxidative stress, pain, and delayed healing. To overcome the limitations of conventional photosensitizers, which may induce reactive oxygen species (ROS) overload and…

Adv Sci (Weinh). 2026 Jun 22:e76240. doi: 10.1002/advs.76240. Online ahead of print. ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria-cancer cell interface. Proximity…