Educating and Building a Broader Biocatalysis Community
Angew Chem Int Ed Engl. 2026 Aug 19:e5014162. doi: 10.1002/anie.5014162. Online ahead of print. ABSTRACT Biotin-streptavidin artificial metalloenzymes (ArMs) provide a platform to integrate transition-metal catalysis within a protein-defined microenvironment. Traditional indolone syntheses often rely on transition metal catalysts, high temperatures, and strong oxidants, limiting functional-group tolerance, and sustainability. In this study, we report a…
Molecules. 2026 Jul 28;31(15):2626. doi: 10.3390/molecules31152626. ABSTRACT The chronic overuse of antibiotics has accelerated the emergence of antibiotic-resistant bacteria, creating a global public health crisis as conventional therapies fail against multidrug-resistant pathogens spreading through water and food chains. Cadmium sulfide (CdS) has been established as an important visible-light-driven photocatalyst for antibacterial applications. This brief review…
J Am Chem Soc. 2026 Aug 12;148(31):33757-33766. doi: 10.1021/jacs.6c11128. ABSTRACT We report a tetrazine-regulated in situ hydrazine release strategy to synthesize highly crystalline azine-linked COFs (AZ-COFs) with varied central cores (triazine, cyanuric acid, benzene). The slow hydrolysis of 3,6-dimethyl-1,2,4,5-tetrazine enables controlled hydrazine generation, allowing kinetically moderated azine formation and overcoming crystallization challenges. The triazine-centered AZ-COF-1…
J Hazard Mater. 2026 Aug 10;515:143227. doi: 10.1016/j.jhazmat.2026.143227. Online ahead of print. ABSTRACT To address the challenge of simultaneously achieving efficient removal, enhanced mineralization, and risk mitigation of dimethyl phthalate (DMP), a multifunctional sodium alginate (SA) microbead platform integrating photocatalysis, enzymatic catalysis, and magnetic recovery was developed. A CeO2@Bi2WO6 heterojunction was first constructed, and the…
Luminescence. 2026 Aug;41(8):e70600. doi: 10.1002/bio.70600. ABSTRACT Zinc oxide nanoparticles (ZnO NPs) were successfully synthesized via an eco-friendly green route using aqueous leaf extract of Sonchus wightianus as a natural reducing and capping agent. UV-Vis spectroscopy revealed a characteristic absorption peak at 267 nm, with a direct optical band gap of 2.96 eV and an Urbach…
Angew Chem Int Ed Engl. 2026 Aug 5:e5802081. doi: 10.1002/anie.5802081. Online ahead of print. ABSTRACT Photocatalytic hydrogen peroxide (H2O2) synthesis via oxygen reduction reaction (ORR) offers a sustainable alternative to energy-intensive anthraquinone processes. However, its efficiency is hindered by poor selectivity and instability stemming from reactive superoxide intermediates through the two-step two-electron (2e–) route. Herein,…
J Physiol. 2026 Jul 28. doi: 10.1113/JP290658. Online ahead of print. ABSTRACT Fibroblasts have emerged as inflammatory entities in ulcerative colitis (UC) and eosinophilic oesophagitis, positioning these cells as attractive therapeutic targets. Previous studies have shown that hydroxylase inhibitors elicit anti-inflammatory responses, but their effects on fibroblasts during inflammation remain unknown. Here we test the…
Metab Eng. 2026 Jul 25:102506. doi: 10.1016/j.ymben.2026.102506. Online ahead of print. ABSTRACT Flavonolignans are pharmacologically important plant natural products whose production has been limited to extraction from natural sources. Their defining transformation, the oxidative coupling of flavonoid and phenylpropanoid precursors, was demonstrated to be enzyme-catalyzed. Here we show that milk thistle flavonolignans can also be…
Adv Sci (Weinh). 2026 Jul 20:e76698. doi: 10.1002/advs.76698. Online ahead of print. ABSTRACT Lignin, the largest renewable aromatic carbon reservoir, represents a foundational yet underutilized feedstock for sustainable biomanufacturing. Despite decades of effort, its effective integration remains constrained, not only by inefficient depolymerization but critically by the lack of coordinated control across depolymerization, conversion, and…
Nanomaterials (Basel). 2026 Jul 4;16(13):823. doi: 10.3390/nano16130823. ABSTRACT This work reports the development of innovative enzyme-titanium nanobiohybrids synthesized via a protein-assisted approach to obtain efficient and sustainable photocatalysts for environmental remediation. By addressing the limitations of conventional TiO2 nanoparticle synthesis, this strategy enables controlled material properties under milder, potentially scalable conditions for enhanced ROS-driven degradation…